Emilio Russo Selected Research

Absence Epilepsy (Childhood Absence Epilepsy)

5/2022	mGlu3 metabotropic glutamate receptors as a target for the treatment of absence epilepsy: preclinical and human genetics data.
5/2022	N-acetylcysteine aggravates seizures while improving depressive-like and cognitive impairment comorbidities in the WAG/Rij rat model of absence epilepsy.
10/2020	IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy.
1/2020	Effects of Histone Deacetylase Inhibitors on the Development of Epilepsy and Psychiatric Comorbidity in WAG/Rij Rats.
1/2020	Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors.
10/2019	Antiepileptogenic effects of Ethosuximide and Levetiracetam in WAG/Rij rats are only temporary.
10/2017	Fingolimod Exerts only Temporary Antiepileptogenic Effects but Longer-Lasting Positive Effects on Behavior in the WAG/Rij Rat Absence Epilepsy Model.
1/2017	Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy, and comorbid depressive-like behavior.
9/2016	The Anticonvulsant Activity of a Flavonoid-Rich Extract from Orange Juice Involves both NMDA and GABA-Benzodiazepine Receptor Complexes.
6/2015	Antidepressants but not antipsychotics have antiepileptogenic effects with limited effects on comorbid depressive-like behaviour in the WAG/Rij rat model of absence epilepsy.

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Emilio Russo Research Topics

Disease

72	Seizures (Absence Seizure) 06/2022 - 02/2003
70	Epilepsy (Aura) 06/2022 - 02/2003
27	Absence Epilepsy (Childhood Absence Epilepsy) 05/2022 - 09/2005
11	Neoplasms (Cancer) 03/2020 - 05/2009
10	Rheumatoid Arthritis 01/2018 - 01/2013
8	Drug-Related Side Effects and Adverse Reactions 01/2020 - 02/2013
7	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2016
7	Inflammation (Inflammations) 04/2021 - 04/2015
7	Status Epilepticus (Complex Partial Status Epilepticus) 11/2019 - 06/2011
6	Cognitive Dysfunction 05/2022 - 01/2016
5	Neuroinflammatory Diseases 10/2021 - 11/2014
5	Temporal Lobe Epilepsy 08/2020 - 01/2015
5	Insulin Resistance 04/2018 - 05/2015
4	Psoriasis (Pustulosis Palmaris et Plantaris) 05/2021 - 12/2013
4	Stroke (Strokes) 01/2021 - 04/2013
4	Brain Diseases (Brain Disorder) 01/2021 - 04/2015
4	Mental Disorders (Mental Disorder) 04/2020 - 06/2013
4	Nervous System Diseases (Neurological Disorders) 11/2017 - 09/2012
4	Multiple Sclerosis 01/2017 - 04/2013
3	Generalized Epilepsy 05/2022 - 10/2018
3	Idiopathic Generalized Epilepsy 05/2022 - 12/2016
3	Chronic Renal Insufficiency 01/2022 - 01/2016
3	Chronic Kidney Failure (Chronic Renal Failure) 05/2021 - 01/2018
3	Sleepiness 01/2021 - 01/2021
3	Hypoglycemia (Reactive Hypoglycemia) 12/2020 - 01/2018
3	Fibrosis (Cirrhosis) 01/2020 - 09/2011
3	Pain (Aches) 01/2020 - 06/2013
3	Psoriatic Arthritis 01/2018 - 12/2013
3	Hippocampal Sclerosis 11/2017 - 01/2015
3	Reflex Epilepsy (Photosensitive Epilepsy) 12/2016 - 03/2016
3	Parkinson Disease (Parkinson's Disease) 11/2016 - 04/2013
3	Schizophrenia (Dementia Praecox) 01/2015 - 09/2007
2	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2022 - 01/2021
2	Cysts 01/2022 - 01/2021
2	Hypertension (High Blood Pressure) 11/2021 - 09/2019
2	Ulcerative Colitis 07/2021 - 01/2019
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2021 - 01/2020
2	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 05/2021 - 01/2021
2	Obesity 01/2021 - 11/2020
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2021 - 01/2021
2	Atrial Fibrillation 01/2021 - 01/2015

Drug/Important Bio-Agent (IBA)

36	Pharmaceutical PreparationsIBA 05/2022 - 08/2008
34	Anticonvulsants (Antiepileptic Drugs)IBA 08/2020 - 02/2003
11	perampanelIBA 02/2022 - 03/2014
11	AMPA Receptors (AMPA Receptor)IBA 01/2020 - 05/2004
8	Antidepressive Agents (Antidepressants)IBA 06/2022 - 07/2011
8	Insulin (Novolin)FDA Link 12/2020 - 01/2016
8	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2020 - 02/2003
7	CannabidiolIBA 01/2022 - 01/2016
7	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 01/2016
7	Valproic Acid (Depakote)FDA LinkGeneric 01/2020 - 02/2013
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2015
6	Antipsychotic Agents (Antipsychotics)IBA 05/2021 - 09/2008
6	Biological ProductsIBA 04/2020 - 01/2017
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2020 - 04/2013
5	Pentylenetetrazole (Metrazol)IBA 01/2019 - 02/2003
5	AcidsIBA 01/2018 - 02/2003
4	brivaracetamIBA 02/2022 - 01/2015
4	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 01/2016
4	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2021 - 12/2013
4	Butyric Acid (Butanoic Acid)IBA 01/2020 - 01/2019
4	Kainic Acid (Kainate)IBA 11/2019 - 02/2003
4	Levetiracetam (Keppra)FDA LinkGeneric 10/2019 - 08/2010
4	Carbamazepine (Tegretol)FDA LinkGeneric 05/2018 - 07/2011
4	Abatacept (Orencia)FDA Link 04/2018 - 12/2013
4	Complement C3 (C3 Complement)IBA 01/2018 - 01/2016
4	CannabinoidsIBA 11/2017 - 09/2013
4	Tryptases (Tryptase)IBA 10/2015 - 01/2013
3	Immunoglobulin E (IgE)IBA 05/2022 - 03/2016
3	Lacosamide FDA Link 02/2022 - 01/2016
3	CenobamateIBA 02/2022 - 01/2021
3	methylglyoxal bis(3-aminopropylamidinohydrazone)IBA 01/2022 - 01/2021
3	Transaminases (Aminotransferases)IBA 01/2021 - 12/2014
3	CytokinesIBA 10/2020 - 11/2014
3	SuspensionsIBA 10/2020 - 08/2014
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 06/2013
3	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020 - 01/2016
3	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 01/2017
3	Ethosuximide (Zarontin)FDA LinkGeneric 10/2019 - 08/2008
3	Methotrexate (Mexate)FDA LinkGeneric 01/2018 - 01/2013
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 01/2015
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2016 - 06/2013
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2016 - 12/2012
3	TOR Serine-Threonine KinasesIBA 01/2016 - 06/2013
3	Sirolimus (Rapamycin)FDA Link 11/2014 - 06/2013
3	Lamotrigine (Lamictal)FDA LinkGeneric 10/2013 - 02/2013
3	2- acetyl- 1- (4'- chlorophenyl)- 6,7- dimethoxy- 1,2,3,4- tetrahydroisoquinolineIBA 08/2008 - 01/2004
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 06/2022 - 06/2015
2	Fluoxetine (Prozac)FDA LinkGeneric 06/2022 - 06/2015
2	Sertraline (Zoloft)FDA LinkGeneric 06/2022 - 01/2016
2	Glutamic Acid (Glutamate)FDA Link 05/2022 - 01/2020
2	eslicarbazepine acetateIBA 02/2022 - 12/2017
2	PrebioticsIBA 01/2022 - 10/2021
2	ixekizumabIBA 05/2021 - 01/2020
2	MineralsIBA 04/2021 - 01/2021
2	Cathepsin KIBA 04/2021 - 01/2021
2	AnticoagulantsIBA 01/2021 - 01/2018
2	edoxabanIBA 01/2021 - 01/2018

Therapy/Procedure

37	Therapeutics 05/2022 - 05/2012
6	Aftercare (After-Treatment) 05/2021 - 04/2015